DIARRHOEA MANAGEMENT IN DAIRY ANIMALS
Defination :
It is a condition in which liquid faeces is passed frequently without constitutional disturbance. It indicates something wrong with intestines or depressing influence in the intestines. It is itself not a disease but merely a symptom of some disease.
Diarrhoea is a multifactorial disease entity that can have serious financial and animal welfare implications in dairy herds. It has been estimated that 75% of early calf mortality in dairy herds is caused by acute diarrhoea in the pre-weaning period
Diarrhoea is a common complaint in cattle and young ruminants (particularly in the first few months of life). Many of the pathogens and management practices that cause diarrhoea in calves also affect lambs and goats. Most herds are exposed to diarrhoea causing pathogens, and management practices will largely determine the health impact that those pathogens will have on the youngstock. In “real life”, most young ruminant diarrhoea is caused by more than one factor or pathologic agent. It is important to be able to correctly diagnose and appropriately treat diarrhea in livestock, and to be able to suggest management strategies that will prevent further outbreaks of disease. Several pathogens are zoonotic agents (Salmonella spp., Cryptosporidium spp., Giardia spp., and certain types of enteropathogenic E. coli) so great care must be taken when handling diarrheic animals, contaminated bedding, and fecal samples to avoid contaminating yourself and others.
Causes :
As enteritis, sudden change of diet, mouldy, rancid or fermenting material etc.
Symptoms:
Frequent passing of liquid stool. Sometimes blood stained. Dull, depressed and mild abdominal pain. Ordinarily there is no temperature but high temperature in specific diseases. The continuous diarrhoea is serious because absorption of nutrients is impaired and loss of fluid gives rise to dehydration. If the treatment is not undertaken in time, there is often death. The laboratory examination of faeces will reveal the causing agent
DYSENTERY :
Defination :
It is a condition in which liquid consistency of faeces is discharged with blood and mucous at frequent intervals accomplanied by pain and tenesmus.
Causes :
It is mostly associated with some specific diseases e.g. Haemorrhagic septicaemic, Anthrax, Rinder pest, coccidiosis Amoebiasis, ulceration and inflammation or rupture of blood vessels of intestines etc.
Symptoms :
Discharge of liquid stool with blood and mucous at ferquent intervals and straining during defecation. The blood may be fresh or back in colour. Appetite decreased but not off feed. Pain in abdomen due to pressure on belly. The temperature may be elevated or high in specific diseases. The animal becomes weak, dull and depressed. In severe continuous conditions, there is dehydration and anaemia. If the treatment is not undertaken in time, it causes fatal.
ENTERITIS :
Defination :
It is the inflammation of intestines. The intestines comprises of various parts and the inflammation of each has separate terminology e.g.
• Duodenum Duodenitis
• Ileum Ileitis
• Caecum Typhilitis
• Colon Colitis
• Reetum Proctitis.
Enteritis may be either specific or non-specific nature. It is common in all animals
(i) Specific Nature :
It occurs in specific diseases with specific causes e.g. Rinder pest, foot and mouth disease. johne’s disease, tuberculosis, lamb dysentery swine fever etc.
(ii) Non-specifitc Nature :
It resembles to those conditions which are found frequently in gastritis. Thus, the combined conditions of gastritis and non-specific nature are called Gastor-Enteritis.
CAUSES :
• Succulent green fodder or frosty food or cold.
• Irritants-e.g. foreign bodies, poisonous plants, grasses and vegetables etc.
• Poisons-e.g. Arsenic. Lead, mercury etc.
• Bacterial disease e.g. H.s anthrax, Braxy, Johne’s diseases, salmonellosis, lamb dysentry, white scoute, swine erysipelas etc.
• Viral diseases-e.g. Rinder pest, foot and mouth disease, Distemper, swine fever etc.
• Parasites and protozoa e.g. flukes, Haemonchus, ostertegia, Gastrophilus, Ascardiae, coccidae, amoeba etc.
Symptoms :
Diarrhoea and dysentery, dehydration in serious condition and absorption disturbed due to less chemical changes.
In Cattle :
There is persistent diarrhoea with progressive anaemia, faeces thin and watery often blood stained, variable temperature, high temperature in specific diseases, no temperature in parasitic and poisoning cases, progressive wasting in prolonged cases, rapidly fatal suspects malicious poisoning.
In Horse :
Dullness with continuous abdominal pain manufested by restlessness, constipation in beginning but later on followed by diarrhoea, pulse small and hard, respiration not interfered, mucous membranes congested, condition due to parasites usually appear during autumn, winter and early spring and is serious for young colts, faeces often thin, watery with offensive odour, abdomen slightly pendulous and oedema of the dependent parts. In delayed conditions, it may prove fatal due to excessive loss of power and anaemia.
In Dogs :
Frequent passing of watery stool with offensive smelling, intermitent vomitting, high temperature in specific diseases, convalescence in puppies may be seen
DIARRHOEA :
Implications of Diarrhoea
When an animal passes watery droppings many times a day it has diarrhoea.Animals with diarrhoea have certain symptoms like
Lose water and salt from their bodies.
Animals become weak and thin
Loss of appetite
Lose watery feaces contains mucous and sometimes blood comes along with feaces
Loss of milk production and animals can die if treatment gets delayed
Common causes of diarrhoea
Diarrhoea may be occurred due to Physiological and Pathological causes:
Physiological causes of diarrhoea are mainly
• Increase in intestinal peristalsis
• Hyper secretion of intestinal fluid
• Damage to intestinal mucosa
• Malabsorption
• In diarrhoea, the intestine fails to adequately absorb fluids, and/or secretion into the intestine is increased. Loss of fluids through diarrhoea produces dehydration and the loss of certain body salts. Diarrhoea causes a change in body tissue composition and severe depression in the animal.
Etiology of diarrhoea- On the basis of etiology diarrhoea can be classified as infectious and non-infectious diarrhoea
Causes of diarrhoea can be broadly divided into two categories
- Infectious diarrhoea- Infectious diarrhoea can be caused by agents like virus, bacteria, parasites, mycotoxins etc.
- Non infectious diarrhoea- Non infectious diarrhoea can be caused due to poor hygiene, stress, overfeeding, indigestion, faulty diet, intestinal injury and inflammation and malabsorption.
• Possible causes include bacterial and viral infections, certain chemicals, intestinal parasites, poor diet, overfeeding on milk or lush grass, poisonous, plants and other toxins, food allergies and even stress.
• In diarrhoea, the intestine fails to adequately absorb fluids, and/or secretion into the intestine is increased. Loss of fluids through diarrhoea produces dehydration and the loss of certain body salts.
• It causes a change in body tissue composition and severe depression in the animal.
• Death from scours is usually the result of dehydration and loss of body salts rather than invasion of an infectious agent.
The correct determination of the cause of diarrhoea is important in order to take effective preventive measures.
Infectious diarrhoea and its management in calf
About 80% deaths due to diarrhoea occur in the first 6 months of calf life. The main cause of death in acute diarrhoea is dehydration which results from loss of fluid and electrolytes in diarrhoea stools. Diarrhoea is an important cause of malnutrition. This is because calf with diarrhoea eat less and their ability to absorb nutrients is reduced; moreover their nutrient requirements are increased as a result of infection.
Viral diarrhoea
Rotavirus diarrhoea
a. Within 24 hours of birth, a germ called rotavirus causes this type of diarrhoea.
b. Infected calves are severely depressed. There may be drooling of saliva and watery diarrhoea.
c. The faeces will vary in colour from yellow to green.
d. Calves lose appetite and the death rate may be as high as 50 %.
e. There are no signs on dead animals; however, there is an increased volume of fluid in both the small and large intestine.
Coronavirus diarrhoea
a. This occurs in calves that are over 5 days of age; the germ is called coronavirus.
b. The animal is not as depressed as in rotavirus diarrhoea.
c. The initial signs may be the same as in rotavirus, but later on the faeces may contain clear mucus that resembles the white of an egg.
d. Mortality is low (1-25 %).
a. Diarrhoea begins 2 to 3 days after exposure to the germ and may persist for a long time.
b. Ulcers on the tongue, lips and in the mouth are the usual lesions found in the live calf.
c. Bovine virus diarrhoea is controlled by vaccinating all replacement heifers 1 to 2 months before breeding.
d. Pregnant heifers should not be vaccinated. Consult your state veterinarian before starting a BVD vaccination programme.
Bacterial diarrhoea
Colibacillosis (Eschericia coli)
Eschericia coli is a major cause of diarrhoea in young calves. E. coli germs attack the intestinal mucous membrane and other mucous membranes and produce toxins (poisons).
The toxins cause severe inflammation of the intestinal lining (enteritis) and can lead to death within hours. A less severe form of the disease is usually characterised by diarrhoea accompanied by progressive dehydration. Colibacillosis lasts 2 to 4 days and its severity depends on the age of the calf. E. coli inhabits the intestine and is excreted in the faeces. It can contaminate kraals, stables, floors, paddocks and even water supplies.
Control of E. coli scours can be difficult in a severe herd outbreak. Early detection (as well as isolation of affected animals) and treatment of scours help to prevent new cases. consult your veterinarian or animal health technician for advice on the use of the available remedies, which are usually mixtures of sulphas and antibiotics.
Animals may be vaccinated 6 weeks and 3 weeks before calving. However, the calves must get colostrum in the first few hours of life for the vaccine to be effective.
Salmonella
a. Salmonella germs produce a poison called an endotoxin. Calves are usually affected at 6 days of age or older (the same as in coronavirus diarrhoea).
b. Signs of salmonella scours include diarrhoea, presence of blood and fibrin (yellow clots) in the faeces, depression and elevated temperature.
c. Salmonella germs multiply in the intestine and many reach the bloodstream, causing blood infection and sudden death. Finding a membrane-like cover in the intestine of a dead animal suggests salmonellosis.
d. Tick-borne diseases and underfeeding of calves predispose them to salmonella scours. Heavily infected animals may become severely depressed following treatment with antibiotics because treatment causes the salmonella organisms to release toxins.
Control and treatment of Salmonella diarrhoea
a. Control of E. coli scours can be difficult in a severe herd outbreak. Early detection (as well as isolation of affected animals) and treatment of scours help to prevent new cases. Speak to your state veterinarian or animal health technician for advice on the use of the available remedies, which are usually mixtures of sulphas and antibiotics.
b. Animals may be vaccinated 6 weeks and 3 weeks before calving. However, the calves must get colostrum in the first few hours of life for the vaccine to be effective.
c. Guidelines for colibacillosis control consist of letting cows calve in an uncontaminated environment, e.g. in the veld; ensuring that calves consume enough colostrum and assisting weak calves; feeding or treating cows with a vitamin A preparation during dry periods (winter); keeping calves in clean pens and paddocks; feeding calves out of clean buckets; and the vaccination of pregnant cows.
Enterotoxaemia (pulpy kidney)
a. The disease usually starts quite suddenly. Affected animals become listless, display uneasiness, and strain or kick at their abdomen. Bloody diarrhoea may or may not occur.
b. It is usually associated with change in the weather, a change in the feed of the cows, or management practices that cause the calf to nurse for a longer period of time than usual. The hungry calf may overconsume milk which establishes an environment in the gut that is conducive to the growth and production of toxins by germs.
c. In dead animals the gut may be red in colour or have bloody, purplish areas.
Other causes of calf diarrhoea
Coccidiosis
Coccidiosis occurs in calves of 3 weeks of age and older, usually following stress, poor sanitation, overcrowding or sudden changes of feed.
A typical sign of coccidiosis in young calves is diarrhoea with faeces smeared over the rump as far around as the tail will reach. The symptoms are diarrhoea, with slimy and bloody faeces, emaciation, weakening and anaemia. The affected calves strain excessively when they defecate.
Treatment and control of coccidial diarrhoea
Consult your veterinarian for treatment of the disease with appropriate remedies such as sulphonamides and Amprolium.
Good feeding practices, management and sanitation are possible control options.
Nutritional diarrhoea
a. Nutritional scours are caused by anything that disrupts the normal nursing pattern, for example storms, strong wind or the mother’s temporary absence. When the hungry calf gets the opportunity to nurse, the cow’s udder may contain more milk than normal and the calf may take in excessive quantities, resulting in nutritional scours.
b. It is usually white scours caused by undigested milk passing through the intestinal tract.
c. It usually presents little problems. Milking the cow to limit the milk intake by the calf usually clears up the problem. Oral antibiotics may be used if the calf becomes depressed.
Treatment of calf scours
a. Treatment of the forms of diarrhoea is very similar regardless of the cause.
b. Specific treatment is often not possible and symptomatic treatment of the diarrhoea itself should be applied.
c. It should be directed towards correcting the loss of fluids (dehydration), acidosis (acidity) and loss of salts.
d. Calves may be given milk diluted with an equal quantity of clean water.
e. Antibiotic and or sulpha treatment can be given simultaneously with the treatment for dehydration.
f. There are salt powders (also called electrolyte powders) available that can be mixed with water for oral administration.
Diarrhoea in adult ruminants
Diarrhoea in adult ruminants can be of infectious and non-infectious origin. Infectious diarrhoea in cattle is mainly caused by bacteria, virus and protozoa and non infectious diarrhoea is mainly caused due to dietary error and intestinal diaturbaces.
Infectious diarrhoea in cattle and its management
Johne’s disease or paratuberculosis
Casual agent-Mycobacterium paratuberculosis
Johne’s disease (JD) is a chronic, progressive intestinal disease caused by infection with Mycobacterium paratuberculosis (Map). The agent was first identified in European cattle a century ago, and it was discovered in the United States in the early 1900s. Control of JD has been problematic because it has a long incubation period, it is clinically similar to many other common diseases of cattle, available diagnostic tests are expensive and relatively low in sensitivity, and there are no accepted standards for diagnosis and control. These problems are compounded by a lack of awareness of the disease and the fact that its slow progression makes financial losses not easily perceptible to the individual producer.
Johne’s disease is an incurable wasting disease of adult cattle. It is of greater concern in dairy herds than in beef operations. This difference reflects variations in management practices-especially close confinement in dairy operations, which promotes easier transmission of the organism. The germ causes an infectious inflammation of the intestines with severe weight loss and diarrhoea. It is economically important because some animals may become so emaciated that they are unfit for slaughter.
Johne’s disease should be suspected when, despite persistent diarrhoea, animals continue to eat well and look bright. The manure of typical cases is not mixed with blood or mucus. An adult cow with persistent diarrhoea, lasting for months, that is not responding to treatment, is likely to have Johne’s disease.
Control of JD on farms has been difficult for several reasons. The disease has a long subclinical phase, during which animals can spread the infection without themselves exhibiting signs of illness.
For dairy herds, the recommendations include:
• Taking precautions against introducing the disease through purchased animals
• Isolating and slaughtering clinically infected animals
• Culling recent offspring of clinical cases as soon as possible
• Removing calves from dams immediately upon birth (before suckling)
• Isolating calves in separate calf-rearing area
• Harvesting colostrum from cows with cleaned and sanitized udders
• Feeding colostrum to calves by bucket, and thereafter feeding only milk replacer or pasteurized milk
• Preventing contamination of calf feedstuffs, water, or bedding by effluent from the adult herd
• Applying manure from the adult herd only to cropland or to pastures grazed by adult stock
Prevention and control measures-Infectious disease biosecurity (preventing the introduction of disease to a farm) has two major components:
The first is to reduce the likelihood of introduction of an infectious agent into a group (external biosecurity). The second is to reduce the likelihood of transmission once a disease is present (internal biosecurity or biocontainment).
Other causes of infectious diarrhoea
• Salmonellosis (unusually a wasting disease in adults).
• Bovine virus diarrhoea.
• Protozoal diarrhoea
Treatment of infectious diarrhoea
Various drugs are available in the market for treatment of infectious diarrhoea caused by Bacterial, protozoal and to check secondary infection caused by viral diarrhoea.
Out of all the combinations Norfloxacin and Tinidazole is found to be most effective treatment in bacterial and protozoal diarrhoea. Norfloxacin is a synthetic broad spectrum antibacterial agent belonging to the fluoroquinolone group. It exerts its bactericidal effect by inhibiting the Asubunit of DNA gyrase, an essential enzyme involved in DNA replication. Tinidazole is a nitroimidazole which has antimicrobial action against microaerophilic protozoa Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis and against obligate anaerobic bacteria. It acts by damage of DNA strands or inhibition of their synthesis.
Some proven trials-Efficacy of Norfloxacin
The bacteriological and clinical efficacy of norfloxacin 400 mg b.i.d. was compared to those of co-trimoxazole (160 mg of trimethoprim plus 800 mg of sulphamethoxazole) b.i.d. and placebo b.i.d. for the treatment of acute bacterial diarrhoea in a randomized double-blind trial. Of a total of 450 patients with acute diarrhoea, 303 had positive bacterial cultures and were evaluable for efficacy. The time to elimination of pathogens was significantly (p less than 0.001) shorter in the norfloxacin group than in the co-trimoxazole and placebo groups. At completion of treatment, bacteriological cure was found in 97.9%, 72.4% and 38.2% of patients treated with norfloxacin, co-trimoxazole and placebo, respectively. All pathogens were susceptible to norfloxacin and none of them developed resistance to norfloxacin during treatment. In the co-trimoxazole group, resistance to that antibiotic increased from 2% at inclusion to 65.6% at the end of treatment (p less than 0.001). In patients with shigellosis or cholera, the mean time to normalization of bowel movements was significantly shorter in the norfloxacin and co-trimoxazole groups than in the placebo group (p less than 0.05 and p less than 0.01, respectively). There were no significant differences between groups with respect to adverse events reported. In conclusion, norfloxacin was well tolerated and highly effective in the treatment of acute bacterial diarrhoea.
Lolekha S, Patanachareon S, Thanangkul B, and Vibulbandhitkit S
Non infectious diarrhoea in cattle
Causes-
• Faulty diet
• Inflammation and injury to intestine
• Indigestion and mal-absorption
• Hypersecretion or increased motility in intestine
• overfeeding
Role of herbs in the control and treatment of non-infectious diarrhoea
Non infectious diarrhoea mainly occurs due to dietary error and intestinal disturbances. Herbs possess a great value to restore G.I functions and repair G.I mucosa.
CERTAIN IMPORTANT FEATURES OF HERBS
• Herbs forms protective layer on mucosal surface of intestine and reduces the severity of diarrhoea
• Herbs regulates the peristaltic movements of intestine
• Herbs provides healthy environment for growth and multiplication of micro flora
Some Treatment Recommendations
• A veterinarian or animal health technician should be consulted if possible on the best course of treatment-especially when diarrhoea is severe or persistent.
• Try to determine the cause and then apply appropriate treatment.
• Always administer clean water or barley water at intervals of 2 to 3 hours to compensate for the loss of body fluids.
• Dosing activated charcoal with water may be of benefit in cases of poisoning. Limewater, tannic acid or commercial diarrhoea remedies could be used to
• treat diarrhoea if the animal is in danger of dehydrating. If the diarrhoea is not severe and the animal is not dehydrating it is better to treat diarrhoea with herbal remedies
• Sulphas and antibiotics should only be used on the recommendation of a veterinarian or animal health technician.
HOMEOPATHIC TREATMENT
Dysentery:
Treatment :
- Aconite 30 : Dysentery in early stages, with febrile symptom and in
summer.
Dose : B.I.D. 2 to 3 days - Nux vomica 200 or 1M : Dysentery with blood & mucus.
Dose :B.I.D for 2 days - Merc sol 200: diarrhoea with mucus, stomatitis.
Dose : B.I.D. for 2 days - Merc cor 200 : Diarrhoea with mucus and blood, stomatitis.
Dose : B.I.D for 2 days - When dysentery with pyrexia and offensive in nature combine Merc. Cor 200 with Pyroginum 200 and then administered for quick and good results.
- Arsenic 30 : In early stages, due to food poisoning or when body is
cold. Administered 5 pills or 5 drops every 30 mts, till relief. - Ferrum phos 6x : Dysentery with blood and bad smell. 10 pills for
ever 2 hours - Biochemical combinations :
Calc. phos 3x
Ferrum phos 3x
Kali mur 3x
Mag phos 3x
Nat sulph 3x
Nat mur 3x
Kali phos 3x
The above formula is indicated when dysentery with blood, pyrexia, anorexia, with bad smell. 10 pills of the combination Q.I.D for 2 to 3 days.
- Homeopathic Formula :
Aloe
Antimony crude
Chelidonium Major
China
Croton Tiglium
Nux Vomica
Podophylum aa 3
Each 2ml is mixed with 60 ml of vimeral liquid.
Dose : 5 ml B.I.D. for 2 to 3 days
Indications : 1. Seasonal diarrhoea
- Weaning diarrhoea
- Over eating diarrhoea
- Diarrhoea due to change of feed
- Diarrhoea due to infection
DIARRHOEA :
Treatment :
Simple diarrhoea can be cured, by removing the causative factor, and by giving the animal dry feed.
- Aconitum 30 : In the primary stage, which may be accompanied with fever and inflammation of the bowels.
Dose : Q.I.D - Nux Vomica 30 : This drug is indicated, when the diarrhoea is feculent and
offensive, with rumbling noises while passing flatus. The drug is also useful in cases, where purging and constipation alternate.
Dose : Q.I.D - Arsenicum 30 : Watery, Slimy, Greenish or brownish diarrhoea with or
without griping pains.
Dose : Q.I.D - Merc. sol 30 or 200: Where the diarrhoea is mixed with mucus.
Dose : Q.I.D - China 30 : Indicated, in chronic diarrhoea. painless discharge, loss of appetite,
debility and cachexia. The drug may also be administered when the symptoms have subsided.
Dose : Q.I.D - Veratrum album 30 : Discharges are altogether watery, frequent and
involuntary and the nose, mouth and ear tips are cold.
Dose : Q.I.D - Bryonia 30 : It is indicated where diarrhoea alternates with constipation.
The animal turns his head towards the flank.
Dose : Q.I.D - Pulsatilla 30 : It is the drug of choice in calves. When suckles, enormous
quantity of fatty milk.
Dose : Q.I.D
Compiled & Shared by- Team, LITD (Livestock Institute of Training & Development)
Image-Courtesy-Google
Reference-On Request.
